Th2-Associated Alternative Kupffer Cell Activation Promotes Liver Fibrosis without Inducing Local Inflammation
Cirrhosis is the final outcome of liver fibrosis.Kupffer cell-mediated hepatic inflammation is considered to aggravate liver injury and fibrosis.Alternatively-activated macrophages are able to control chronic inflammatory events and trigger wound healing processes.Nevertheless, the role of alternative Kupffer cell activation in liver harm is largel